Step Inside 111Skin’s Luxe New Spa at The Plaza
New York’s iconic Plaza Hotel has been a temporary home to countless travelers and celebrities. Did you know it’s where the Beatles stayed when they first visited Manhattan in 1964? Then, of course, there’s Eloise, arguably the hotel’s most famous inhabitant. And now the hotel has a permanent—and very luxurious—new resident: the 111Skin Spa/Clinic, a first-of-its kind destination in the US. The Plaza Hotel has partnered with 111Skin to bring the globally renowned skin care authority’s clinically driven, results-focused treatments into an iconic setting.
Rooted in the expertise of founder Dr. Yannis Alexandrides, a renowned reconstructive surgeon, the 111Skin Spa/Clinic offers highly personalized facial and body therapies that fuse advanced clinical technology with restorative rituals. Each experience begins with an in-depth consultation to assess individual skin and wellness needs, followed by bespoke treatments designed to deliver visible, long-term results—whether your goal is recovery, radiance, or a full reset.
© Simon Lewis Studio
© Simon Lewis Studio
Set within The Plaza’s historic walls—a space that also served as the location for Glamour’s 2026 Women of the Year awards ceremony—the spa spans 8,000 square feet and includes relaxation lounges, state-of-the-art treatment rooms, and private wellness suites. From LED light therapy and cryotherapy to hydro-infusion and the brand’s signature Exosome Regenerative Facial, every element is designed to merge science with luxury.
“This is a huge privilege,” says Dr. Alexandrides. “As an extension of my practice at [London’s] 111 Harley St., I couldn’t imagine a more fitting setting to bring our luxurious science-backed treatments to New York.” Sam Ioannidis, managing director at The Plaza, adds, “By uniting innovation in longevity with our legacy of glamour, we’re redefining wellness at The Plaza with the arrival of 111Skin Spa/Clinic.”
© Simon Lewis Studio
The opening also marks a significant milestone for 111Skin, establishing its first permanent US flagship. Between the Plaza Hotel’s legendary afternoon teas, iconic Grand Ballroom events, and its status as a cultural landmark, the spa promises to be a must-visit destination.
Located in the heart of Manhattan, on Fifth Avenue and Central Park South, The Plaza first opened its doors on October 1, 1907. The hotel is 19 stories of glamour and luxury; styled after a French château, it came from the minds of financier Bernhard Beinecke, hotelier Fred Sterry, and Harry S. Black, president of the Fuller Construction Company. The Plaza is now widely considered a cultural institution.
To book an appointment at 111Skin Spa/Clinic, call 212-872-7200 or visit 111skinspa.com.
