AI Is Helping Bring Back the Dodo

“De-extinction is as much a data problem as a biology problem,” said Colossal CEO and co-founder Ben Lamm in a statement. “[AI] learns how regulatory DNA shapes living birds, then identifies the genetic switches that may have contributed to the dodo’s distinctive anatomy.”

Colossal established its de-extinction bona fides in 2025, when it announced that it had sequenced ancient DNA from the long-extinct dire wolf, used that to rewrite the genome of the extant gray wolf, and brought the Ice Age dire wolf back to life, more than 10,000 years after it vanished. Animals that are also on the company’s de-extinction to-do list include the woolly mammoth, the Tasmanian tiger, the ostrich-like moa, and the antelope-like quagga. The dodo, with its waddling gait, its stubby wings, its goggly eyes, and its preposterous beak, has none of the power, grace, or charisma of those other animals—but that’s part of its charm.